Takara RetroNectin特價(jià)促銷(xiāo)活動(dòng)進(jìn)行中 | ||||||||||||||||
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■ 最新優(yōu)秀論文 | ||||||||||||||||
Duo Zhang,Protocol to generate traceable CAR T cells for syngeneic mouse cancer models. | ||||||||||||||||
為回饋廣大科研院所師生對(duì)Takara品牌的支持,促進(jìn)中國(guó)細(xì)胞治療的基礎(chǔ)研究,現(xiàn)公司決定針對(duì)細(xì)胞治療產(chǎn)品RetroNectin® 推出學(xué)生體驗(yàn)價(jià)550元/支,5支起訂,此活動(dòng)2024年3月20日起執(zhí)行,每位客戶(hù)5個(gè)月內(nèi)限購(gòu)1次(參加此活動(dòng)不再同時(shí)享受680元/支特殊優(yōu)惠價(jià)的活動(dòng))。 現(xiàn)常規(guī)促銷(xiāo)價(jià)920元/支,不限購(gòu) 現(xiàn)特殊優(yōu)惠促銷(xiāo)價(jià)680元/支,2支起訂,每位客戶(hù)限購(gòu)2支/月 促銷(xiāo)起始日期:2024年3月20日 促銷(xiāo)截止日期:另行通知 溫馨提示:關(guān)于此產(chǎn)品的訂購(gòu)和技術(shù)疑問(wèn),請(qǐng)致電010-80720983 |
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Retronectin 制備CAR-T部分文獻(xiàn) | ||||||||||||||||
1: Okuma A. Generation of CAR-T Cells by Lentiviral Transduction. 2: Nasiri F . Effects of polybrene and retronectin as transduction enhancers on the development and phenotypic characteristics of VHH-based CD19-redirected CAR T cells: a comparative investigation. 3: Rajabzadeh A.highly enhance the gene transduction efficiency of Mucin-1-specific chimeric antigen receptor (CAR) in human primary T cells. 4:Dan Lu. KRAS G12V neoantigen specific T cell receptor for adoptive T cell therapy against tumors. 5:Chen Wang, Circadian tumor infiltration and function of CD8 + T cells dictate immunotherapy efficacy. 6:Xin Zhang, The cell cycle regulator p16 promotes tumor infiltrated CD8 + T cell exhaustion and apoptosis. 7:Yue Hu,Selective refueling of CAR T cells using ADA1 and CD26 boosts antitumor immunity. 8:Duo Zhang,Protocol to generate traceable CAR T cells for syngeneic mouse cancer models. |
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Retronectin 刺激淋巴細(xì)胞活化擴(kuò)增部分文獻(xiàn) | ||||||||||||||||
1: Zhao L, Clinical value of neutrophil-to-lymphocyte ratio as a predictor of prognosis of RetroNectin-activated cytokine-induced killer cell therapy in advanced non-small-cell lung cancer. 2: Gong W, Evaluation of Production Protocols for the Generation of NY-ESO-1-Specific T Cells. Cells. 3: Zhao L, Pseudoprogression: an indicator for cure in combined immunotherapy? |
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♥ 產(chǎn)品特點(diǎn) | ||||||||||||||||
● 可以將逆轉(zhuǎn)錄病毒中的目的基因高效轉(zhuǎn)入造血干細(xì)胞、T淋巴細(xì)胞等哺乳動(dòng)物來(lái)源的細(xì)胞。 ● 避免感染過(guò)程中因使用polybrene造成的細(xì)胞毒作用。 ● 同樣適用于感染常規(guī)的細(xì)胞系。 ● RetroNectin是重組人纖維連接蛋白片段,包括細(xì)胞結(jié)合域,肝磷脂結(jié)合域和CS1位點(diǎn)三個(gè)功能區(qū)域。它由574個(gè)氨基酸組成,分子量63 kDa。RetroNectin能夠大大的提高逆轉(zhuǎn)錄病毒感染哺乳動(dòng)物細(xì)胞的感染效率,其作用原理是:細(xì)胞表面VLA-4及VLA-5可分別于RetroNectin上的CS-1位點(diǎn)及細(xì)胞結(jié)合域結(jié)合,逆轉(zhuǎn)錄病毒載體可以與肝磷脂結(jié)合域結(jié)合。在經(jīng)RetroNectin包被的培養(yǎng)容器表面,細(xì)胞與病毒載體以高濃度共存,從而提高基因轉(zhuǎn)染效率30%-70%。 ● 另外RetroNectin還可以刺激淋巴細(xì)胞增殖,尤其是胸腹水以及腫瘤組織分離的TIL細(xì)胞,利用RetroNectin技術(shù)均可使其獲得上千倍的增殖,已有部分客戶(hù)將RetroNectin技術(shù)擴(kuò)增TIL的方法進(jìn)行專(zhuān)利申請(qǐng)。 |
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