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10 
 		 Hitting Back at Hepatitis B
(runtime: 2:07 min)		  
 
   
     
  Hepatitis B not only hijacks cells to make legions of new infectious particles, it also establishes long-term infections and leads to hepatocellular carcinoma. Wu and colleagues examined how expression of the oncogenic Hepatitis B virus X protein (HBx) alters miRNA expression in cultured liver cells. Using a PrimeScript RT-PCR kit with green intercalating dye to measure miRNAs via real-time PCR, they observed down-regulation of miR-16 members involved in cell cycle regulation. Reintroducing miR-16 to HBx-expressing cells suppressed key hallmarks of cancer. That's Good Science!™  
     
     

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