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當(dāng)前位置:首頁> 產(chǎn)品選擇指南 > 干細(xì)胞研究相關(guān)制品 > 抗體 (Antibodies) > 監(jiān)控人類細(xì)胞移植用途的抗體Engrafted Cell Markers
監(jiān)控人類細(xì)胞移植用途的抗體Engrafted Cell Markers
品牌 Code No. 產(chǎn)品名稱 包裝量 價格(元) 說明書 數(shù)量
Cellartis Y40400 STEM101 50 μg ¥2,251
Cellartis Y40410 STEM121 50 μg ¥2,281
Cellartis Y40420 STEM123 50 μg ¥2,246
監(jiān)控人類細(xì)胞移植用途的抗體
(Antibodies for Detecting Human Cells Transplanted into Mice and Rats)
STEM101、STEM121、STEM123是三種小鼠來源的單克隆抗體,用于人類細(xì)胞向小鼠和大鼠移植實驗中,監(jiān)控細(xì)胞移植、轉(zhuǎn)移、分化。
 
■ 產(chǎn)品特點
· STEM101 reacts specifically with the nuclear human Ku80 protein; the antibody does not cross-react with mouse or rat Ku80 in brain tissue or cell extracts
Note: STEM101 (Y40400) is not suitable for immunohistochemically staining on paraffin embedded tissue sections. We recommend using fresh frozen tissue with this antibody.
· STEM121 reacts with a human cytoplasmic protein expressed in brain, liver, pancreas, and CNS cells the antibody does not cross-react with brain tissue or cell extracts from mouse, rat, or cynomologous monkey
· STEM123 reacts specifically with human GFAP, a marker of astroglial cells; the antibody does not cross-react with brain tissue or cell extracts from mouse or rat
 
■ 產(chǎn)品應(yīng)用
· Localization, quantification, and/or characterization of engrafted cells of human origin by immunohistochemistry and immunofluorescence
 
 
 
■ 產(chǎn)品詳情請點擊:
 
STEM101 detects nuclei of transplanted human neural stem cells in the olfactory bulb of a mouse brain.
 
STEM121 detects migration and differentiation of transplanted human neural stem cells in the hippocampus of a mouse brain.
 
STEM123 detects human GFAP+ astrocytes differentiated from human neural stem cells after transplantation into a mouse brain.
 
參考文獻(xiàn):
1. Cummings BJ, et al. (2005) Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice. PNAS 102: 14069-14074.
2. Guzman R, et al. (2007) Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI. PNAS 104: 10211-10216.
3. Tamaki SJ, et al. (2009) Neuroprotection of Host Cells by Human Central Nervous System Stem Cells in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis. Cell Stem Cell 5:310-319.
4. Salazar DL, et al. (2010) Human Neural Stem Cells Differentiate and Promote Locomotor Recovery in an Early Chronic Spinal Cord Injury NOD-scid Mouse Model. PLoS ONE 5: e12272.
5. Kelly S, et al. Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex. PNAS (2004) 101:11839 11844.
6. Cummings BJ, et al. Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice. PNAS (2005) 102: 14069-14074.
7. Tamaki SJ, et al. Neuroprotection of Host Cells by Human Central Nervous System Stem Cells in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis. Cell Stem Cell (2009) 5:310-319.
8. Kallur T, et al. Human Fetal Cortical and Striatal Neural Stem Cells Generate Region-Specific Neurons In Vitro and Differentiate Extensively to Neurons After Intrastriatal Transplantation in Neonatal Rats. J Neurosci Res. (2006) 84:1630-1644.
9. Salazar DL, et al. Human Neural Stem Cells Differentiate and Promote Locomotor Recovery in an Early Chronic Spinal Cord Injury NOD-scid Mouse Model. PLoS ONE (2010) 5: e12272.
10. Tamaki SJ, et al. (2009) Neuroprotection of Host Cells by Human Central Nervous System Stem Cells in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis. Cell Stem Cell 5:310-319.
11. Salazar DL, et al. (2010) Human Neural Stem Cells Differentiate and Promote Locomotor Recovery in an Early Chronic Spinal Cord Injury NOD-scid Mouse Model. PLoS ONE 5:e12272.
12. Cummings BJ, et al. (2005) Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice. PNAS 102: 14069-14074.
 

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